Hydration
Helps attract and hold water for a more hydrated, supple-looking complexion.
Sodium Hyaluronate • Sodium PCAIngredients + Technology
The formula is more than an ingredient list.
DermaReverse is organized around two targeted technologies, H2OA and HP4. Each has a distinct role inside one finished serum designed to support smoother, firmer and more hydrated-looking skin.
2Targeted technologies
1Complete water-based serum
6 weeksFinished formula studied
Complex 01
H2OA
Targeted vitamin A technology for visible renewal.
Complex 02
HP4
Complementary peptide support for visible skin quality.
Two complementary roles
Two different jobs. One considered formula.
H2OA leads the visible-renewal story. HP4 brings complementary peptide support. The rest of the formula supports hydration, comfort, radiance and product integrity.
01Visible renewal + smoothness
H2OA
Targeted vitamin A technologyDesigned to support cosmetic renewal and the appearance of smoother, more refined-looking skin.
See what it contains →02Firmness + elasticity + hydration
HP4
Complementary peptide complexDesigned to support the appearance of firmness, elasticity, hydration and fine lines.
See what it contains →Complex 01
H2OA
Targeted vitamin A technology
A focused vitamin A story designed to support cosmetic renewal and the appearance of smoother, more refined-looking skin.
What it contains
Retinol / Water-Soluble Axerophthol
Why it is special
H2OA gives DermaReverse a defined visible-renewal role within a lightweight, water-based serum. It sits beside hydration- and comfort-supporting ingredients rather than being presented as a standalone active.
Cosmetic renewalSmoother-looking skinRefined-looking texture
Daytime use must be followed with SPF 30+ sunscreen. Review the complete vitamin A use guidance below.
Complex 02
HP4
Complementary peptide complex
A peptide-focused system designed to support the appearance of firmness, elasticity, hydration and fine lines.
What it contains
Palmitoyl OligopeptideA skin-conditioning peptide used to support a conditioned, smoother-looking skin feel.
Palmitoyl TetrapeptideA complementary skin-conditioning peptide used to support a conditioned, smoother-looking skin feel.
Why it is special
Rather than relying on a single peptide callout, HP4 brings two complementary peptide ingredients together around one focused role: supporting visibly firmer, more elastic, hydrated and smoother-looking skin.
FirmnessElasticityHydrationFine lines
The supporting system
H2OA and HP4 are the core actives. The complete formula supports comfortable, consistent daily use.
Comfort
Helps support a calm, comfortable-feeling formula.
Aloe Vera Gel • Chamomile • Calendula • AllantoinRadiance
Supports the look of radiance, even-looking tone and healthy-looking skin.
Ascorbic Acid • Ascorbyl Palmitate • Ginseng ExtractFormula integrity
Helps carry, blend, stabilize, preserve and maintain the finished serum.
Water • Lecithin • Carbomer • Cellulose • Guar Gum • Preservatives • Citric AcidThe finished formula
The evidence belongs to the complete serum.
The published study evaluated DermaReverse as one finished formula against a placebo over six weeks.
Explore the clinical studyComplete transparency
Every ingredient, in one place.
View the complete ingredient list
Purified Water, Sodium Hyaluronate, Aloe Vera Gel, Chamomile, Calendula, Ascorbic Acid, Lecithin, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide, Sodium PCA, Carbomer, Hydroxyethyl Cellulose, Ascorbyl Palmitate, Ginseng Extract, Allantoin, Guar Gum, Retinol, Retinyl Palmitate, Phenoxyethanol, Potassium Sorbate, Citric Acid.
Vitamin A use guidance
DermaReverse contains vitamin A-related ingredients. Do not use during pregnancy, nursing or while planning pregnancy. Do not use alongside other topical retinoids unless directed by a licensed medical professional. Apply SPF 30+ sunscreen during the day.
One complete formulation
Meet the complete formula.
One twice-daily serum designed to support visible skin quality without adding four more steps to your routine.