THE DERMAREVERSE CLINICAL STUDY
Clinical research, explained simply.
We believe you deserve a clear look at the research behind the skincare you choose. Here is what the published clinical study measured, and what it found.
Why this matters
Good skincare information should feel clear, not complicated.
In a published clinical study, a topical serum was evaluated in people using GLP-1 receptor agonist or SGLT2-related therapies. The research looked at visible facial skin quality over six weeks.
The serum was used twice daily. Researchers compared it with a placebo, then assessed visible change at the start, at three weeks, and again at six weeks.
Summary of the results
What the study found.
Each result below reflects what was observed in the published six-week clinical study. This is skincare research, not a promise of identical results for every person.
At 3 weeks
Visible improvement was observed.
What this means
The treated side showed visible improvement by Day 21, after twice-daily use.
At 6 weeks
Even greater improvement was reported.
What this means
Additional improvement was observed at the Day 42 final
A closer look
Visible skin quality was assessed side by side.
The study compared DermaReverse with a placebo over six weeks, then evaluated both sides of the face at baseline, at three weeks, and at six weeks.
Across the measured parameters, the treated side showed statistically significant improvement compared with the placebo side. Individual results may vary.
Photographs are of a single study participant and have not been retouched.
WHAT WAS MEASURED
13 dimensions of visible skin quality.
The study used the Global Ranking Scale to evaluate the appearance of each side of the face across these parameters.
01 • Loss of elasticity
Skin that feels less firm and does not bounce back as easily.
02 • Surface roughness
Skin texture that looks or feels uneven, coarse, or bumpy.
03 • Dehydration
Skin that lacks water and may look dry, dull, tight, or less plump.
04 • Static wrinkles
Lines and wrinkles that are visible even when the face is relaxed.
05 • Dynamic wrinkles
Lines that appear or become more noticeable when making facial expressions.
06 • Volume loss
A reduction in facial fullness or plumpness that can create a hollow appearance.
07 • Sagging
Skin and facial tissue that appear to droop or sit lower than before.
08 • Asymmetry
Noticeable differences between the left and right sides of the face when viewed from the front.
09 • Imbalance
Facial features or proportions that appear less harmonious when viewed from the side.
10 • Scar presence
How noticeable or prominent existing facial scars appear.
11 • Visible pores
Pores that appear enlarged or easy to see.
12 • Pigmentation
Uneven skin color, including dark spots, discoloration, or blotchiness.
13 • Vasculature
Visible redness or small blood vessels showing through the skin.
Built to make the comparison more meaningful.
When You Are Ready
Bring evidence into your everyday routine.
Explore the formula, how to use it, and whether DermaReverse feels right for your skincare routine.
Explore DermaReverseQuestions about the research, answered.
FOR READERS WHO WANT THE SOURCE MATERIAL
Read the peer reviewed published article.
A Single Center, Blinded, Placebo Controlled Study Evaluating Cosmetic Efficacy and Safety of a Novel Topical GLPSGLT in Glucagon Like Peptide 1 Analog Treated Patients.
Published in Aesthetic Surgery Journal Open Forum, 2025.